Nona Biosciences

Nona Biosciences is a global biotechnology company committed to providing a total solution for partners worldwide, from academies, biotech startups to biopharma giants. The integrated antibody discovery services range from antigen preparation, animal immunization, single B cell screening, to antibody lead generation and engineering, developability assessment and pharmacological evaluation, leveraging the advantages of Harbour Mice® platforms and the experienced therapeutic antibody discovery team.

Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format. Integrating Harbour Mice® and a single B cell cloning platform, Nona Biosciences is focused on driving global inventions of transformative next-generation drugs by diversified partnership strategies. The values of the antibody discovery platforms and flexible partnership models have been well validated.

Our Mission

Leveraging industrial leading Harbour Mice® platforms, Nona Biosciences is committed to providing a total solution for biotech and pharmaceutical companies from Idea to IND (I to ITM).

Core Technology:
Harbour Mice®
New Generation of Fully Human
Antibody Platforms

A unique platform to generate human heavy chain only antibodies naturally suitable for making bispecific antibodies

  • Unique fully human sequence HCAb
  • Versatile for broad applications, incl. CART, ADC, mRNA and diagnostic imaging tool etc.

Transgenic mice bearing human preferential immunoglobulin genes with robust B cell development & antibody maturation

  • Robust and highly efficient
  • Global IP
  • Clinically validated
Next-Generation Therapeutic Modalities
  • HCAb +antibody/protein
  • HCAb +payload
  • HCAb +cell
  • HCAb +nanoparticle
Discovery Solution
A one-stop solution for therapeutic antibody
discovery, engineering and development.
  • Antigen Design,
    Production & Cell
    Line Generation
  • In Vitro Functional
    Assays Establishment
  • Harbour Mice®
    H2L2, HCAb
  • Beacon® Single B
    Cell Screening
  • Display Technologies
    Phage, Yeast & Mammalian Cell (Optional)
  • Recombinant
  • In Vitro
  • In Vivo PK/PD
    Efficacy Study
  • Developability
  • Antibody Engineering
    Affinity Maturation, Liability Engineering, Fc Engineering
  • Bispecific
Flexible Business Models
We are here for you, embracing and supporting
brilliant ideas, and building your corridor to success.
Versatile Business Solutions to Maximize the Value of Customers
  • Platform LicenseTARGET
  • Platform + Antibody DiscoveryCANDIDATE
  • Co-Discovery PartnershipASSET
H2L2 and HCAb Harbour Mice® Platforms have been well
validated and widely used in the industry & academia.
1 Broadway, Cambridge, MA 02142
(+1) 617-4108904
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